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Shana Kelley & Ted Sargent – Introduction to Nanotechnology: The New Science of Small

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Shana Kelley & Ted Sargent – Introduction to Nanotechnology: The New Science of Small
Introduction to Nanotechnology: The New Science of Small

Zoom in on a world where distances are measured in billionths of a meter—the fascinating science of nanotechnology.
LECTURE
Trailer
01:The Crossroads of 21st-Century Science

Join Professors Sargent and Kelley for an initial plunge into the nanoscale, the tiny and mind-blowing realm where revolutionary developments are taking place in applied physics, computer science, biology, and medicine. Begin by probing the size of a nanometer and consider how laws of nature and principles of design change at that scale.

34 min
02:The Fundamental Importance of Being Nano

Professor Sargent discusses the rules that govern the nanoscale, where the strange effects of quantum mechanics offer exciting possibilities for engineering. Survey the structure of atoms and molecules and their interactions with light, which are fundamental properties at the nanoscale.

31 min
03:From Micro to Nano—Scaling in a Digital World

Trace the evolution of the original computer switches—vacuum tubes—to smaller and smaller components: first to discrete transistors and then to printed circuits that have now shrunk to the nanoscale. Learn how Moore’s law predicts exponential progress in this “race to the bottom.”

29 min
04:Leveraging the Nanometer in Computing

Moore’s law forecasts that the number of transistors on an integrated circuit will double roughly every two years. This rule of thumb has held for more than half a century. But how long can it continue? The nanoscale offers new challenges and solutions to the problem of producing ever-smaller circuits.

30 min
05:Leveraging the Nanometer in Communications

How did the world become networked so fast? Follow a beam of light down a fiber-optic cable to understand why it now costs pennies to send data that would have been billed at more than $100,000 just a few decades ago.

32 min
06:Sensing the World through Nanoengineering

Megapixel cameras on cell phones may seem miraculous, but nanoengineering promises far more powerful imaging systems. Quantum dots will give cameras much greater sensitivity and the ability to detect light across a broad range of invisible wavelengths, opening new applications for image processing.

33 min
07:Nanomedicine—DNA and Gold Nanoparticles

Begin a series of lectures with Dr. Kelley on nanoscience in biology. The building blocks of life, including DNA, are nanoscale objects, making ideal targets for nanotechnology diagnostic tools and disease treatments. As an example, see how gold nanoparticles are used to identify genetic mutations.

29 min
08:Nano and Proteins—Enzymes to Cholesterol

Gold nanoparticles attached to an antibody protein allow a simple pregnancy test. Discover that nanoparticles are also tools for mapping how cholesterol and other protein molecules enter cells.

29 min
09:Nanoparticles Detect Cancer in Living Organisms

Learn how metal nanoparticles called quantum dots can signal the presence of cancer cells inside the body. While still experimental, this technology may herald a breakthrough in noninvasive medical imaging.

28 min
10:Detecting Only a Few Molecules of a Disease

Turn to cancer diagnostic tools “in vitro”—outside the body. Professor Kelley discusses her own work on a system for disease diagnosis that uses nanomaterials layered on microelectronic chips. This research promises much more efficient detection of the molecules that signal cancer.

29 min
11:Nanomaterials That Seek and Destroy Disease

Explore three strategies for treating tumors. A photothermal approach places gold nanoparticles in a tumor and then irradiates the particles from an external source. A similar but more targeted technique tunes the radiation to a precise frequency, sparing surrounding tissues. Finally, learn how the gold nanoparticles themselves can be the tumor-killing agent.

29 min
12:How Nanomaterials Improve Drug Delivery

Drugs are administered by injection, inhalation, skin patches, or in pills. These methods deliver only a fraction of the medication to the needed areas, and many potentially useful biomolecules have no effective way to get to their targets. Discover that nanomaterials offer a solution to these problems.

30 min
13:Delivering Drugs with “Smart” Nanocapsules

Learn how nano-enabled drug delivery systems can target cells with greater potency and fewer side effects than traditional treatments can. Examples include protein nanoparticles and liposomes, which have already been approved for clinical use. Then examine some next-generation approaches.

29 min
14:Nanoscale Surgical Tools

Nanoscale surgical tools can make excisions with incredible precision, ensuring that when a cancerous tumor is removed, no malignant cells remain and no healthy cells are harmed. Explore this ongoing medical revolution, and discover the role of robotics in enhancing the surgeon’s skill.

27 min
15:Nanomaterials for Artificial Tissue

Regenerative medicine focuses on producing artificial substitutes that can restore or replace damaged tissues or organs. Learn how nanomaterials stimulate cell and tissue growth in the body. Also follow progress in generating artificial organs outside the body to help meet the demand for organ transplants.

30 min
16:How Nano Research Gets Done

Professors Kelley and Sargent introduce their research teams. Discover that nanotechnology is highly interdisciplinary. Chemists generate new materials. Physicists help understand those materials. Biologists put biomolecules and nanomaterials together. And engineers help turn basic discoveries into devices.

34 min
17:Nanomotifs—Building Blocks, Complex Structures

Professor Sargent takes a brief interlude to showcase the visual side of nanoengineering. View the complex structures that are built from nanoparts. Starting with nanoparticles, consider the many shapes that can be created, from nanotubes to supercrystals—structures that are not just useful but beautiful.

32 min
18:Using Nanotechnology to Capture Sunlight

Starting a sequence of lectures on nanotechnology and energy, Professor Sargent probes the physics of solar cells, which use semiconductors to generate an electric current from sunlight. Learn how nanotechnology is making this renewable energy source more efficient and cost-effective.

30 min
19:Photons to Electricity—Nano-Based Solar Cells

Explore further into nanoscale solar cell technology by looking at different techniques for capturing solar energy. Rigid silicon-based hardware may soon be a thing of the past, replaced by inexpensive products such as organic photovoltaics, which are composed of physically flexible organic polymers that can be applied like plastic sheeting.

32 min
20:Nanotechnology for Storing Energy

One of the challenges of renewable energy is that its hours of peak production may not correspond to times of peak demand, creating the problem of energy storage. Investigate some solutions that nanotechnology offers, including supercapacitors and a remarkable new class of batteries assembled by viruses.

30 min
21:Nanotechnology for Releasing Energy

Catalysts foster a chemical reaction without being consumed by the reaction, using and releasing energy with incredible efficiency. Explore this phenomenon at the nanoscale, seeing how nanomaterials can increase the surface area of a catalyst, which greatly improves its performance for a wide range of applications.

30 min
22:Energy’s Holy Grail—Artificial Photosynthesis

The ultimate energy collection and storage system is photosynthesis. Nature does it with plants, but researchers are striving to attain the same result with nanotechnology—using sunlight to produce and store energy in the form of a fuel such as hydrogen.

31 min
23:Nanorobots and Nature’s Nanomachines

Learn how nanorobots that take over the world in science fiction usually defy the laws of physics, and survey concerns about the harm that nanomaterials can do. Look at nanovehicles built with buckeyballs for wheels, and then turn to nature’s nanomachines such as diatoms, which build astonishing structures at the molecular level. Explore ways that these tiny creatures may be more effective than nanorobots.

30 min
24:On the Horizon and in the Far Future

Close your exploration of nanotechnology by looking ahead at possible near- and long-term developments. One is a real “cloak of invisibility.” Then look back to revisit physicist Richard Feynman’s bold predictions. See how far we’ve come and discover what Feynman apparently overlooked.

37 min
DETAILS
Overview
Nanotechnology is today’s most powerful engine of innovation, turning cutting-edge research into applications at an astonishing rate. Now, in the 24 accessible and visually rich half-hour lectures of Introduction to Nanotechnology: The New Science of Small, get an in-depth explanation of this groundbreaking, interdisciplinary science that operates at the level of atoms and molecules. You’ll learn about once-fantastical applications that are transforming tools, products, and services in the communications, technology, medical, energy, and engineering worlds, and that hold great promise for meeting some of society’s greatest challenges.
About
Shana Kelley

As you might imagine, nanoscientists derive lots of inspiration from biology. We look at the complex world of biology and we marvel at its ability to selforganize and we try to recreate what we see with the tools of nanotechnology.
Dr. Shana Kelley is the former director of the Division of Biomolecular Sciences at the Leslie Dan Faculty of Pharmacy at the University of Toronto. She earned her Ph.D. in Chemistry from the California Institute of Technology. Professor Kelley’s research has been featured in Scientific American and Nature Medicine, among other publications. Her work has been recognized with a variety of awards, including a National Science Foundation CAREER Award, a Sloan Research Fellowship, and a Camille Dreyfus Teacher-Scholar Award. She currently serves as Chief Technology Officer for a firm she cofounded, which is based on her work in biomolecular sensing.
Ted Sargent 

Our capability to understand and engineer materials on the nanoscale has enabled the computer revolution.

Dr. Ted Sargent holds the Canada Research Chair in Nanotechnology in The Edward S. Rogers Sr. Department of Electrical and Computer Engineering at the University of Toronto, where he also earned his Ph.D. His research has been disseminated in leading scientific journals, and he is the author of The Dance of Molecules: How Nanotechnology Is Changing Our Lives. In 2007 he addressed the pathbreaking Technology, Entertainment, Design (TED) Conference in Monterey, California. Professor Sargent founded and serves as Chief Technology Officer and a director of InVisage Technologies Inc., which was honored with The Wall Street Journal 2010 Technology Innovation Award.
REVIEWS
beth1708

Interesting information

I enjoyed learning more about nano tech. I’m looking forward to seeing such things come on line in the world we see.
Berniek 

Excellent Course

Professors, Drs Sargent and Kelley a husband-and-wife team, are able to make an extremely complex field understandable to a layman with the level of high physics. One could take the course many times and glean more information each pass. They present the material interestly not just dry physics.